The creatinine test is used to evaluate glomerular filtration function and monitor kidney progress.
Some of the drugs before using for patients, doctors need to know if the kidney function is safe to use or not, so it is necessary to test the body function test, Creatinin before using the drug. This is a good job for the health of the patient, and also helps the doctor to closely listen to the patient's body listening.
The conversion between phosphocreatine and creatine is a characteristic process of muscle contraction. The ratio of free creatinine in muscle (about 1-2% / day) transforms into a natural and unchanged waste product, which is creatinine. Therefore, the amount of creatinine produced per day is stable and is related to muscle mass (more men than women). In healthy people, blood creatinine levels are always stable. Creatinine is present in bodily fluids, excreted and completely filtered by the glomeruli
Therefore, the daily production of creatinine depends on muscle mass and is completely excreted by the kidneys
Creatinine can be measured in blood and urine, from which creatinine clearance can be calculated to assess the kidney's filtering function.
The creatinine test is indicated when there is a suspicion that the kidney is not working well and is often used in conjunction with urea to evaluate the kidney's filtering function or level of kidney failure.
. It can also be ordered during a routine health check to evaluate conditions or in case of a kidney transplant, creatinine testing is important in monitoring transplant rejection.
High blood creatinine has been shown to have kidney problems or causes of kidney function such as:
Before the kidney: reduce blood flow to the kidneys such as dehydration, shock, congestive heart failure ...
In the kidneys: glomerular damage, glomerulonephritis are caused by infections, hypertension, diabetes, lupus erythematosus, lead poisoning, mercury,
After the kidneys: obstruction of the urethra due to kidney stones, bladder tumors, prostate tumors, ..
Increased blood creatinine can also be caused by muscle trauma, muscle diseases such as giant, limb enlargement, ..
Decreased creatinine is rarely mentioned, mainly in cases of decreased muscle mass.
Creatinine excreted in the urine of men is usually higher than women and increases with age.
Determination of creatinine clearance factors allows a better assessment of renal function.
To measure kidney function, the blood urea / creatinine ratio can be used, normally the ratio is from 6: 1 to 20: 1
Before taking any drug, it is necessary to evaluate the concentration of urea and creatinine in the blood to avoid nephrotoxicity.
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