Crp (c Reactive Protein) Assay
Quantitative CRP test in serum or serum to determine inflammation and monitor response to infection.
What is CRP?
CRP is an acute phase reagant, a protein produced by the liver and released into the blood within hours of tissue damage, infection, or other cause of inflammation. CRP levels increase significantly with trauma, heart attack, autoimmune disorders, and cause serious bacterial infections such as sepsis. CRP levels may increase over a thousand times in response to inflammation, and an increase in CRP may be preceded by pain, fever, or other clinical signs. A test that measures the amount of CRP in the blood is valuable for detecting acute inflammation or monitoring progression of chronic diseases
The CRP test is not for diagnosis, but it does provide information about the presence of infection. This information combines with other factors, such as signs, clinical examination symptoms, and other tests, to determine whether a patient has an acute inflammatory condition or is experiencing an outbreak. Chronic inflammatory disease
Where is the CRP test indicated?
A CRP test may be ordered when a serious bacterial infection is suspected based on medical history and other clinical signs and symptoms. CRP may be prescribed by a doctor when an infant shows signs of infection or when a patient has symptoms of sepsis, such as fever, chills, shortness of breath and fast heart beat.
CRP can also be prescribed on a regular basis for doctors to monitor rheumatoid arthritis and lupus, CRP is also often repeated over a period of time to determine the effectiveness of treatment. This is useful for assessing inflammation, as CRP levels decrease, so does inflammation.
In what cases does CRP increase?
If the CRP in the blood rises above 10 mg / l, it is the result of an infection or other medical condition, which is not helpful in assessing cardiovascular risk. for disease prevention and for additional diagnosis. In those cases, repeat testing should be done after 2 weeks or after the infection has resolved, to reevaluate the patient's cardiovascular risk
In the quantitative CRP results, CRP index increases, it is necessary to think of a number of acute inflammatory reactions such as acute pancreatitis, CRP ≥ 150 mg / L is severe acute pancreatitis, appendicitis; bacterial infection; Get a burn; rheumatoid arthritis; heart attack; Increased risk of colon cancer CRP levels may also increase during late pregnancy, using birth control pills or hormone replacement therapy (for example, estrogen). Higher concentrations of CRP have also been observed in people with obesity.
A high level of CRP in the blood indicates that the body has an infection but it is unable to determine the location and cause of inflammation. High CRP levels are usually bacterial infections.
. If high CRP levels in chronic inflammation prove ineffective treatment. If CRP decreases, the response to treatment is shown.
Testing of erythrocyte sedimentation rate (ESR) will also increase during the inflammatory phase. However, CRP increases earlier and then decreases faster than the ESR test
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