Gama Glutamyl Transferase (ggt) Test
GGT is an enzyme found in many organs such as kidney, spleen, liver and pancreas. However, the liver is the main source of GGT in the blood. GGT increased in: acute damaged liver or bile ducts. Therefore, the use of GGT is controversial.
Some medications to treat helminths and parasites can increase liver enzymes, if not prescribed by a specialist and monitored regularly, will lead to the use of antihelminthicides that accidentally increase GGT in the blood for a long time. will lead to liver cell damage. Therefore, the selection of drugs and the appointment of GGT tests periodically will help keep the liver healthy.
The level of GGT in the blood is highly sensitive to changes in liver function
The causes leading to liver damage
However, the GGT test is not a specific test.
Drinking a small amount of alcohol can increase GGT. The higher elevations are found in chronic alcoholism, which is aggravated by those who consume two to three glasses of alcohol a day or who drink heavily only at party parties (drunk). The GGT test may be used in assessing an acute or chronic alcohol abuse.
A GGT test may be ordered when there is a high ALP level, to help identify the cause of high ALP due to bone disorder or liver disease
GGT may be ordered along with other tests to monitor Some common signs and symptoms of liver damage include:
Weak health, fatigue. Yellow skin. Itching
Loss of appetite.
. Abdominal swelling or pain.
The urine is dark and the stools will be pale.
GGT increases in most diseases that cause acute damage to the liver or bile ducts, but are often not helpful in distinguishing between different causes of liver damage. It is only useful in determining the cause of elevated ALP
GGT test for alcohol abusers, to monitor compliance with disease treatment programs.
A high level of GGT may indicate a cause of liver damage but no cause. GGT is elevated in diseases such as liver damage or other conditions such as congestive heart failure and alcohol consumption. High levels of GGT will help eliminate some of the causes of ALP increase due to bone disorders.
If GGT is low or normal, but elevated ALP, it is most likely caused by bone disease. A low or normal result does not eliminate the person from liver disease or the person's absence of alcohol.
GGT increased in:
Cholestasis, acute cholecystitis. Pancreatitis Acute and chronic hepatitis, cirrhosis of liver, pancreas, prostate, breast, kidney, lung, brain, ...
Alcoholic liver disease.
Heart failure due to obstruction, acute myocardial infarction.
Smoking can also increase GGT.
GGT levels will increase in older women, men with GGT levels are always higher than women.
Medication: Medications that can increase GGT levels include: phenytoin, carbamazepine, and sedatives like phenobarbital.
Too many prescriptions include nonsteroidal anti-inflammatory drugs, lipid-lowering drugs, antibiotics, histamine receptor blockers, antifungal drugs, antidepressants, etc.
If you drink a small amount of alcohol, GGT levels may temporarily increase within 24 hours. If this occurs try testing again after 24 hours. GGT levels may rise in heart failure. Several studies have shown that people with increased GGT levels are at a higher risk of death from heart disease, but the reason is not known.
GGT reduction: when using clofibrate and oral contraceptives.
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