Is Balantidium Coli Precious Disease?

BALANTIDIUM COLI FACIAL DISEASE
Balantidium coli is a unit belonging to the hairy coat (Ciliata), parasitic in the large intestine, isolated mainly from pigs, who are just accidental hosts, so the disease is classified as active disease. parasite.
In addition, on the basis of immunodeficiency, the disease often progresses severely with a high mortality rate, so B. coli is also an agent of opportunistic infections.
1

. BALANTIDIUM COLI BATH DISEASE
B. Coli has the largest size among intestinal parasitic cells, including active form and cystic form.
Be active
Egg shaped, very variable size, about (30-150µm) x (25-120µm)
The whole body is covered with many rows of fuzz, arranged vertically, helping identical hairs to move The head is tapered, has a funnel-shaped cytostome, the round head has a triangular cytopyge. B.


Is Balantidium Coli Precious Disease?

.coli has two nuclei: a large pea-shaped nucleus and a small, rounded nucleus, located on the concave face of the large nucleus. In the cytoplasm, there are two vacuoles spasm, one in the middle, one near the posterior pole, and many are vacuoles.
Cystic form
Round or ovoid shape, diameter 40 - 65µm, surrounded by two crust, thick outer layer, firm, help cysts well resistant to the environment. When a follicle is newly formed, the undercoat still exists but then gradually escapes. structures such as sporangia, excretory holes, vacuoles also disappear, leaving the nucleus and vacuoles to contract

2 BALANTIDIUM COLI'S FLOW DISEASE DEVELOPMENT PROCESS
People get infected by swallowing cysts by drinking water, dirty food or hands. In the stomach, the capsule's shell is broken down, the active form is released, symbiotic in the intestine or invaded into the intestinal mucosa by secreting the enzyme hyaluronidase and some other protein-destroying enzymes. B.coli exists mainly in the cecum, colon, sigma colon, rarely in the ileum.


Is Balantidium Coli Precious Disease?

. They grow by cz1ch dividing the nucleus and the cytoplasm, however, sexual reproduction can occur in culture. Their nutrients include tissue and intestinal substances such as red blood cells, white blood cells, bacteria, fungi, helminth eggs, unicellular types, starches, and mucus, including congeners. When faced with adverse conditions such as a lack of belching water or when leaving the host body, the active form will become cysts.
The active form develops in anaerobic or aerobic conditions but is highly sensitive to pH <5 and only lasts a few hours outdoors With a temperature of 22◦C in a humid environment, the shelf life can only last a few weeks for cysts and 10 days for active bodies. Therefore, the active form can become contagious if it is exposed to conditions of poor stomach acidity. 3. EPIDEMIOLOGICAL CHARACTERISTICS OF BALANTIDIUM COLI Pigs are the main museum of B.coli. In addition, mice and some other mammals are also hosts of this single cell.

Is Balantidium Coli Precious Disease?

. Natural sources of germs include water, soil, vegetables contaminated with pig or human excrement. Therefore, the habit of drinking uncooked water, eating raw vegetables not washing thoroughly, not washing hands before eating are risk behaviors of infection Flies and cockroaches are also considered as intermediaries for B.coli transmission.
The disease is prevalent all over the world with an estimated infection rate of 0.02% - 1%, which varies greatly depending on the region due to the following factors: i) contact with pigs'; ii) inappropriate handling of faeces resulting in the spread of pathogens into the environment; iiii) a tropical, subtropical climate suitable for follicles that persist in nature; iv) personal hygiene, food hygiene. In hei farming areas, about 25% - 29% of fecal samples are positive for human samples such as in the Philippines, Latin America, New Guinea, Bolivia, some countries in the Middle East.
In Vietnam, some authors recorded B.coli infection rate before 2000 was 0.12%, but today, this number has not been updated.


Is Balantidium Coli Precious Disease?


4. Clinical manifestations of BALANTIDIUM COLI
Although the prevalence of B.coli is high in pigs, 60% - 100%, it is rare in humans. In addition, more than 50% of infections have no clinical manifestations, especially in people who have frequent contact with pigs, and the disease is often severe on immunocompromised muscles with a high mortality rate, around 30 %.
Therefore, it is more likely that a natural immune mechanism exists in humans and immune activity is associated with the severity of the disease. The microflora in the digestive tract also affects the growth of B.coli. After cystic drainage, the active organism takes a while to adapt to the bacterial population in the gut The virulence of B.coli and other factors such as carbohydrate-rich diet, comorbidities, alcoholism, infections, parasites in the gastrointestinal tract also affect the pathogenicity of this kind of flagellum.


Is Balantidium Coli Precious Disease?

.
In the case of clinical manifestations, the disease may be chronic, acute or acute, in which the chronic form predominates with mucous diarrhea, without pus or blood, about 3 - 15 times / day, then self-limited, entering a period of silence from a few days to several months.
The acute form is characterized by signs: premature sadness,.

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