Summary Of Worm Medicines On The Market Today

Infection with helminths is always a threat to people's health, currently parasitic helminths make up 25% of the world's population, mainly concentrated in tropical and subtropical countries or developing countries. .
Currently, it has been identified more than 100 species of nematode and more than 140 species of potentially pathogenic on the human body. Currently there are drugs used to treat common helminths and high efficiency as follows
1. Albendazole 200mg, 400mg
Currently, Albendazole is a common drug in treating parasitic worms

. Albendazole is a carbimate benzimidazole derivative.
The medicine is used to treat with many types of worms such as roundworm, pinworm, hair worm, hookworm, beakworm, eel worm, helminth, etc. eggs / larvae of parasitic worms in the blood or digestive tract Albendazole kills roundworm eggs and hair worms
When using Albendazole may experience some unwanted side effects, but mild transient when taking medication such as abdominal pain, diarrhea, dizziness, tiredness, insomnia.
High-dose, prolonged treatment for cysts or tapeworm larvae with brain damage, more common and severe adverse effects: headache, vomiting, nausea, abdominal pain, loose stools or fertilization, alopecia, neutropenia, liver dysfunction .



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Do not use for pregnant women, children under 1 year of age, people with severe liver disease and according to the prescription of the doctor, patients do not arbitrarily buy medicine to avoid drug allergies or experience severe side effects that last severe. .
2 Mebendazole 500mg
The drug is highly effective when acting on the adult and larval stages of dog roundworm, roundworm, pinworm, hair pinworm, hookworm, beakworm Mebendazole also kills the roundworm and hairworm eggs. In high doses, the drug has an effect on parasitic cysts in the body
The mechanism of action of mebendazole reduces the nutrient uptake of the parasite resulting in immobilization and death of the parasite.
Absorption increases with Mebendazole during meals because of its fat content. The drug is well tolerated, has few side effects.



. Sometimes digestive disorders (abdominal pain, diarrhea), mild headache.
When used in high doses to treat cysts, the drug can cause bone marrow suppression, excessive hair loss, menstrual disorders, liver and kidney dysfunction, fever and peeling.
Therefore, when used in high doses, regular monitoring of transaminase levels in serum, leukocytes and platelets. Do not use mebendazole for people who are sensitive to the drug, pregnant women, children under 2 years of age, liver failure, acute hepatitis
3. Thiabendazole 500mg
Thiabendazole is a medicine to treat worms, which can kill many types of worms: Dog roundworm (dog), hookworm, roundworm, strongyloidworm, hookworm, beakworm, hairworm, dog and cat worm , pinworm.
The mechanism of action of thiabendazole not only prevents the production of eggs, larvae, prevents the development of eggs, larvae in the human body but also prevents the development of eggs or larvae when it is excreted in faeces .
In humans, thiabendazole is absorbed fairly quickly and reaches its maximum concentration in the blood after taking about 1-2 hours. In 48 hours, about 5% of an oral dose is found in faeces and 90% in urine. Most drugs are eliminated in the first 24 hours.



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Thiabendazole is used only for cases that have been diagnosed by blood test, not as a prophylaxis of helminths.
Currently, thiabendazole is not a preferred treatment due to its many side effects, only used when other common drugs fail
Common side effects: dizziness, headache, drowsiness, digestive disorders (loss of appetite, nausea and vomiting, abdominal pain, bloating, diarrhea), chills, numbness in the arms and legs, Dry eyes look blurred, urine has an unpleasant odor. More serious side effects may include: Hypotension, irritability, behavioral disorders, skin rashes, color disorders, jaundice or yellow eyes, dry eyes, dry mouth, dry mouth and joints.
4. Ivermectin 3mg, Ivermectin 6mg
Ivermectin is a semi-synthetic cahats of 1 of avermectin, isolated from Streptomyces avermitilis, the drug works with many roundworms such as roundworm, pinworm, hookworm, hookworm and threadworm, especially effective on Strongyloides stercoralis strongyloid larvae and Onchocera volvolus filariasis larvae show signs of subcutaneous migration.
Ineffective drug treatment on adult worms only, unable to treat fluke worms like liver fluke, tapeworm ...
The mechanism of action of ivermectin is to cause worm paralysis, which results in the worm being expelled and died.




Common side effects can be pain sensitivity in the lymph nodes, more sweating, body aches, swelling of the face, hypotension ... so patients should clearly state their health status to the doctor.
The drug should not be used for children under 5 years of age, pregnant women and nursing mothers. Doctors will consider using medication for patients if the situation really needs.
In addition, there are currently other antihelminthic drugs such as pyrantel, diethylcarbamazin that are less commonly used and specific remedy for specific worms.

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