Depression During Pregnancy

Translation: Nguyen Van Anh, Tran Thi My Hanh
Proofreading: BS. Hoang Bao Nhan
"Children whose mothers are pregnant are more likely to have developmental delays," The Daily Mail reported. The article writes about a study showing that the risk of mental-motor retardation in children whose mothers have depression during pregnancy can be up to 34%, and this risk can be up to 50% if the mother also suffered from postpartum depression.
Previous studies have shown a link between postpartum depression and infant development, and the goal of this study was to find out if there was a correlation between depression during pregnancy and development. child development or not

. Although the findings pointing to the relationship between depression and a child's developmental delay are complex. This study cannot conclude that depression at any time is a cause of growth retardation because a child's developmental delay has many other causes such as health, genetics and social / environmental issues.
The children in this study were only examined once when they were 18 months old, and the developmental delay at this age cannot reflect the child's development in the future.


Depression During Pregnancy


Mothers who are depressed during pregnancy or postpartum should not worry too much that their pathology can cause later developmental delays. This study highlights the frequency of depression in pregnancy and early motherhood; It also emphasizes the need for health care providers to be alert for signs of depression, and to ensure that mothers and their babies receive the necessary care and support.
So where do these conclusions come from?
This research was conducted by Dr. T Deave from the Center for Children's and Adolescent Health - University of the West of England, colleagues from the Department of Social Medicine - School Psychiatry, and Health Center. and Adolescent Health - University of Bristol. The research was supported by the UK Medical Research Council, Wellcome Trust and the University of Bristol, who led a postdoctoral fellowship fellowship in the UK from the University of the West of England. The study was published in the British Journal of Obstetrics and Gynecology

How is this study designed?
In this prospective cohort study, the study aims to examine the relationship between maternal depression in pregnancy and the development of children at 18 months of age.


Depression During Pregnancy


This study uses data from the Avon Parent and Child Follow-up Study (ALSPAC) to follow a large sample in the Avon region, Western England. That study followed mothers during pregnancy and after birth as well as their babies.
The study selected all pregnant women between April 1991 and December 1992 - a total of 14,062 babies. Socioeconomic information, family information and other data (not specified in this report) are collected at weeks 18 and 32 of pregnancy.
The women filled out the 10-question answer sheet (Edinburgh Postnatal Depression Scale - EPDS) at weeks 18 and 32 of pregnancy. This questionnaire is often used to assess postpartum depression by having women assess their emotions for the past seven days, and then give a total score between 0 and 30. The higher the EPDS score, the aggravating symptoms. The women completed the questionnaire again at 8 weeks and 8 months postpartum.


Depression During Pregnancy

Only single pregnant women were included in the study.
The researchers divided the women in the study into three groups of antenatal depression: those with a total score lower than the EPDS depression threshold, who had a score greater than or equal to the one-off threshold (by week week). 18 or 32 of pregnancy), and those with scores greater than or equal to twice the depression threshold during pregnancy. Three different thresholds were used to analyze the data: 9 or 10 points, 12 or 13 (standard threshold) and 14 or 15 points. The researchers say they used different thresholds to reflect the continuity of the data.
Developmental delays in children are assessed using a modified version of the Denver Development Screening (DDST), which their parents have completed. DDST is a screening questionnaire that identifies cognitive and behavioral problems in preschoolers. The test looks at a child's development compared to their age.


Depression During Pregnancy

The more items a child does, the greater the risk of developing developmental delay. Children are considered to be retarded if they do not complete more than one item in the questionnaire.
Statistical tests are used to find the relationship between depression, growth retardation and other factors, including maternal depression, pre-pregnancy depression, father's depression and anxiety, gender, ethnicity, demographic and life events in the previous year.
What are the research results?
The studies were conducted on 11,098 pregnant women with a full prenatal record, of which 44% were pregnant compared with the fetus. Women who do not have adequate data will be excluded.

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