How To Treat Gout And Combination Diseases?

Question: My dad is 56 years old this year. He had gout for 7 years, recently discovered suffering from cardiovascular disease. Please ask, does gout treatment affect the heart? And how to use the drug? Thu Hoa (Nam Dinh)
Reply:
Hyperuricemia (AU) is influenced by genes and food. Research in China also shows that men with high consumption of soft drinks (soda) lead to a very high risk of gout.
Increased primary AU, plays the role of the GLUT gene (Transfert Glucose - the gene that transports glucose or fructose) and many other genes participate

.
Hyperinsulinemia decreases urate excretion and leads to an increase in AU. Use of purine-rich foods, spirits leads to increased urate production and increased uric acid synthesis.
Most gout patients have blood uric acid levels> 416
5 Mmol / l.


How To Treat Gout And Combination Diseases?

The European Association of Rheumatology (EULAR) recommendations aim to treat gout as a reduction in uric acid below 360 Mmol / l.
Treatment of gout, attention should be paid to the treatment of combination diseases. Patients with hypertension should stop using diuretics and use losartan to treat hypertension. Patients with hyperlipidemia should have a reasonable diet, accompanied by use of drugs belonging to the fenofibrat or atorvastatin group.
Gout attacks: ice, colchicine, nonsteroidal anti-inflammatory drugs, topical corticosteroids, ACTH and cytokine resistance.
Treatment of reducing blood uric acid: The goal of treatment is AU <360Mmol / l (recommended by EULAR). Reasonable diet, stop the drugs that cause hyperemia
Use drugs that reduce AU blood.

How To Treat Gout And Combination Diseases?

Colchicine or nonsteroidal anti-inflammatory drugs in the first month. Lifelong treatment.
Drugs that decrease uric acid: inhibit AU synthesis (allopurinol and febuxostat). Increased diuretic AU and oxydaze urate.
-Allopurinol is an inhibitor of Xanthin oxydase synthesis, effectively depends on the therapeutic dose, starting with a low dose and then gradually increasing. You should take your doctor to a specialized hospital for examination, diagnosis and indications for specific treatment..

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