After Treatment For Breast Cancer, What To Note?
Question: My wife, who has had breast cancer, received surgery, radiation and chemotherapy, and has been prescribed medicine for 3 years. The disease is stable but in recent periodic examinations, the blood test for CA 15-3 is higher than normal (40, 48, 80). Please ask, what is the significance of CA 15-3 for breast cancer? Any reason to increase or decrease this index. (Pham Tran Thuong - Hanoi)
Treatment of breast cancer
Answer: CA 15-3 (biomarkers) is primarily used to monitor breast cancer treatment. Typically, biological biomarker tests are performed at the time of diagnosis before, during and after treatment
The CA 15-3 (biomarker) index is primarily used to monitor breast cancer treatment
The amount of CA 15-3 decreases after treatment is effective but may increase temporarily for the first few weeks due to the release of cancer cells when killed by treatment
CA 15-3 may be elevated in other cancers and benign breast diseases, hepatitis. Some cases of breast cancer (breast cancer) after treatment have a rise in CA 15-3 in the blood for some time before clinical manifestations of recurrence.
There is currently no evidence that initiating treatment as soon as an increase in CA 15-3 increases survival efficacy. Therefore, recurrent breast cancer is diagnosed and managed based on clinical symptoms or mammograms (X-ray) usually appear 6 months later than CA 15-3.
Recurrent breast cancer is managed based on mammograms that appear 6 months later than CA 15-3
In case your wife tests for CA 15-3, it appears to be increasing but still within normal limits, so it is necessary to continue to periodically monitor this index and screen for breast cancer, combined with mammogram and examination. Clinical findings for early detection of disease recurrence, from which the doctor will be appointed for further treatment.
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