Decompensated Cirrhosis: Warning Danger Of Life

Decompensated cirrhosis is end-stage cirrhosis, with dangerous complications that can even affect the lives of patients. So how long does cirrhosis decompensate for how long and how to treat to prolong life for patients? Follow the article below to get the necessary information.
What is decompensated cirrhosis?
Decompensated cirrhosis, or ascites cirrhosis, is the final stage of cirrhosis. At this time, the liver cells, liver tissue have been fibrosized, not working properly, leading to seriously impaired liver function. Non-fibrosized liver cells that cannot function to compensate for the fibrosis are called decompensated cirrhosis

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The liver condition at this stage of fibrosis is seriously damaged, unable to recover, regenerate new cells. Therefore, the treatment also plays a role in reducing symptoms, preventing dangerous complications, prolonging life for patients.
Symptoms of decompensated cirrhosis
In the early stages of the disease, undeveloped liver cells can compensate for fibrosis cells (called compensated cirrhosis) so the liver is still functioning normally, the symptoms are not clear But due to undetected, timely treatment, cells continue to be damaged, rapid fibrosis, at this time the symptoms of decompensated cirrhosis will manifest clearly, typically as follows:
Decompensated cirrhosis is a very serious condition that can be life threatening
Internal bleeding
Visceral hemorrhage is a common symptom of decompensated cirrhosis, according to statistics, up to 50% of patients encounter this symptom when diagnosed decompensated cirrhosis.



The reason is that the veins in the liver's portal dilate, bulge, rupture, causing bleeding.
Abdominal distention - ascites
Another common symptom in decompensated cirrhosis is abdominal distention - ascites, which accounts for 85%. This is the condition of the abdomen of the patient, which is increasingly enlarged, the abdominal skin is tight, conspicuous, the blood vessels under the skin of the abdomen emerge, making the patient uncomfortable and painful.
Edema
Another common symptom is edema in decompensated cirrhosis. The cause is fibrous liver cells, impaired liver function, not purifying and excreting toxins out. Therefore, water and fluids will accumulate, causing patients to have lower extremities edema, even more severe than the whole body edema.
Gold eyes, skin
The most noticeable symptoms with the naked eye are jaundice, yellowing of the eyes At the stage of cirrhosis decompensation of the skin, eyes, possibly nails, feet will turn yellow turmeric.



The reason is due to severe impaired liver function, the amount of bilirubin will accumulate in the skin, eye mucosa leading to jaundice, yellow eyes.
Hepatic encephalopathy
When the decompensated cirrhosis situation worsens, the person will develop symptoms of hepatic encephalopathy, also known as hepatic encephalopathy. The reason is that the liver loses its detoxification and detoxification function, causing many toxins to build up in the blood, especially ammonia, leading to an increase in the concentration of ammonia in the blood and brain.
When this symptom appears, the patient has changes in behavior, gradually losing consciousness, body weakness, blurred vision, fatigue ... If not intervened in time, this symptom can be life threatening. sick people's network.




Cirrhosis can cause bloating and bloating
Causes of decompensated cirrhosis
The main cause of decompensated cirrhosis is undiagnosed cirrhosis, which is treated promptly leading to worsening condition, which leads to the final stage of decompensated cirrhosis. Typical causes are:
- Due to the viral hepatitis virus (Hepatitis B, C), this is the main cause of cirrhosis and decompensated cirrhosis.
- Due to excessive use of alcohol, beer, cigarettes causes the liver to overload, continuous operation to purify and eliminate toxins, leading to impaired liver function, liver cell destruction, causing cirrhosis, cirrhosis decompensated liver.
- Fatty liver not caused by alcohol
There are also other causes such as:
- Due to iron accumulation in the body, excess iron, or high iron content (hemochromatosis); Cystic fibrosis; Copper accumulation disease in the liver (Wilson); Diseases related to bile such as obstruction, primary biliary tract inflammation, primary sclerosing cholangitis ...; Genetic metabolic disorder (galatose or glycogen); Hereditary digestive disorders (alagille); Due to drugs such as: methotrexate (Rheumatrex), amiodarone (cordarone) and methyldopa (Aldemet)
Complications of decompensated cirrhosis
Decompensated cirrhosis is a period of severe impaired liver function, unable to recover and regenerate new cells. Therefore causing many complications, such as:
Cirrhosis of the liver
Cirrhosis causes the liver to be unable to synthesize proteins and blood, causing fluid retention, increasing pressure and reducing capillary permeability.



In addition, the amount of albumin in the blood decreases, causing water and other components to enter the abdominal cavity and cause edema. At this time, the belly is becoming bigger and bigger, containing more fluid so the skin is tight, the blood vessels are prominent. The greater the ascites fluid in the abdominal cavity, the more the pressure in the abdomen will cause the patient pain and discomfort.
Gastrointestinal bleeding
As mentioned above, 50% of patients diagnosed with ascites cirrhosis will experience complications of gastrointestinal bleeding due to dilatation and rupture of veins of the esophagus and aneurysm..

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