Food “spoils” Medicine

Some foods may increase the side effects or reduce the therapeutic effects of the drug. Interactions between medication and food are usually indicated in the medication guide. So be sure to read the medication instructions carefully to avoid any possible interactions.
Grapefruit juice
Grapefruit juice can significantly increase the absorption of the drug in the body.
There are two groups of drugs that are particularly noticeable: Blood cholesterol lowering medications: grapefruit juice when taken with simvastatine or atorvastatine can increase the drug's absorption by up to 15 times and cause serious muscle side effects

. .
Immunodeficiency drugs used to fight graft rejection (tacrolimus, ciclosporine .


): when used with grapefruit juice regularly will be toxic to the kidneys.
Patients should be advised to avoid grapefruit juice within 2 hours after taking these medications and should drink less than 250ml of grapefruit juice daily. Conversely, it should be known that apple and orange juice do not interact with the drug.
Foods rich in vitamin K
Eat very little of these foods while taking oral anticoagulants (anticoagulant purposes). These foods reduce the therapeutic effect of the drug so the risk of thrombosis increases (creating blood clots in the lumen). Therefore, during oral anticoagulants, one serving of vegetables should be reduced daily and should not abruptly change your daily eating habits (such as eating more or eating less of the foods you are used to).

Alcohol must be avoided for all drugs that have a neurological effect that reduces alertness such as: sedatives (benzodiazepine anxiety medications), pain or cough medicines containing codeine or tramadol, Neuropathy, antidepressants, and classic anti-histamine antihistamines.


When used concurrently with these drugs, alcohol can cause drowsiness and impair reflexes, which is especially dangerous when driving vehicles or machines. In addition, taking alcohol with non-steroidal anti-inflammatory drugs or aspirine can cause gastric irritation or increase gastric acid secretion.
The citrus fruits
Like lemons, grapefruit, oranges ... Avoid sharing citrus fruits with anti-inflammatory drugs or aspirin, due to aggravation or irritation of the stomach or increased stomach acid.
Anti-inflammatory drugs should be taken with meals to mix with food to reduce side effects on the stomach.
The coffee
Caffeine should be avoided while taking quinolone antibiotics such as enoxacine, ciprofloxacine and norfloxacine or theophylline (asthma medications have the same effect as caffeine).


These antibiotics prevent caffeine excretion and therefore can cause caffeine overdose, leading to irritation, palpitations, tremors, sweating and even hallucinations.
For theophylline, caffeine increases the side effects of theophylline. Therefore, avoid all foods, drinks, such as coffee, tea, or soft drinks containing caffeine during the time on antibiotics or are treating asthma with theophylline.
Licorice root causes hypertension. It should be reduced or better avoided avoiding licorice (candy or licorice drinks) when having high blood pressure. The above are some examples to show that it is necessary to carefully read the medication guide sheet at the start of any medicine to comply with the medication conditions..

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