Medicine To Treat Wounds And Ulcers

Long-lasting ulcers are an obsession of many patients due to radiation therapy for cancer, diabetes, traffic accidents, long-term patients ... Long-term ulcers cause pain, guilt and annoyance for many patients. in daily activities

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What are wounds, sores?
The wound may be due to mechanical causes, burns or chemical causes. Ulcers can be caused by a number of diseases, when lying down for a long time, changing position, common position in the buttocks, shoulder blades, heels, ankles and ulcers due to neuropathy.
Ulcer due to lying down, lying in a position that causes prolonged compression of the skin causing ischemia Leg ulcers are caused by venous failure or ischemia, peripheral nervous system disease, such as diabetes or leprosy.



Many wounds, especially long-term ulcers, cause nuisance and difficulties in care and treatment.
Treatment can be divided into 3 phases:
- Stage of hemostasis immediately after the injury.
- Stage of granulation and epithelial regeneration.
- Skin remodeling and shaping phase.
Hemostasis forms clumps of platelets and clots of fibrin, agglomerates and regenerates the next epithelium and lasts about 21 days after the injury occurs, depending on the width of the wound, where the wound is located. The growth factor produced by platelets stimulates fibroblasts to form granulation tissue, including a collagen matrix, together with capillaries and ingrown epidermal cells, which create epithelium on the surface of the wound.
The collagen matrix strengthens during skin remodeling and reshaping and is accompanied by a reduction in capillaries This period can last up to 2 years from the time of injury.




Treatment of wounds, ulcers
Attention should be paid to a number of important factors: adequate nutrition, especially vitamin C and zinc, needs adequate oxygen and good perfusion. Care should be taken to avoid systemic (or local) infections. Besides is the treatment of these infections.
Certain cell or non-cellular factors such as platelets and growth factors are needed: the lack of these factors also heals the wound. Thus, age, body conditions, medications, nutrition, birth defects all affect the speed of wound healing.
Topical care: Wash, remove inflammatory fluids, prevent infections. The treatment of wounds and the choice of these preparations must be based on the size of the wound, the location of the wound, the type of wound, the shallow or deep and the cause, the infection and the stage of the wound.
Usually use 0.



9% sodium chloride solution, hypochloride, hydrogen peroxide, povidine-iodine, chlorhexidine. Hypocholorids can slow wound healing over the long term because they slow down collagen production and cause inflammation.
Sodium chloride solution is suitable for daily washing of uninfected wounds. There are many cleaning solutions that allow the removal of flakes such as dextranomer, hydrogel, hydrocolloid. Software lysis is effective in removing necrotic tissue.
Wounds can produce large amounts of exudate due to inflammation, especially in the first few days. Hydrocollorid and alginate preparations are effective desiccants.
All wounds have more or less bacteria, when infected with Pseudomonas aeruginosa can make the wound heal long and silver sulfadiazine is used in this case, especially when burned.



It is necessary to treat systemic infections when there is clinical pain such as sudden pain, cellulitis, when waste is increased.
Besides, wound dressing is necessary. Some bandages absorb the inflammatory fluid. Cotton, wool, gauze cannot be used for deep wounds, as there may be fibers that separate and stick to the wound, causing dehydration.
Hydrogels, hydrocolloids, polysaccharides, cadexomer-oids, alginates and foam dressings are suitable products for deep, cavernous, burrowed wounds.
With stench wounds, activated carbon is very effective. Metronidazole has anti-anaerobic activity, which produces a strong pungent odor and is used in addition to eliminating unpleasant odors in tumors (but not in wounds because it can cause drug resistance).
There are also other ways to treat specific wounds or sores, such as draining the fluid from the feet, hanging up the legs, folding the ankles, or using bandages to compress them, all of which are useful in the ulcer.



due to venous insufficiency.
The oral bioflavonoid, oxpentifylin improves the situation of venous insufficiency, leg ulcers, which heals quickly. Topical or systemic ketanserin has been used and proved useful for wounds or sores where insufficient blood flow there or vascular surgery is needed.
Ulcers due to a long position, the reduction of compression is very important. There are some wounds that need skin grafts..

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