Need To Know From A To Z About Autoimmune Hepatitis

Autoimmune hepatitis is recognized as a multisystem disorder that can co-occur with other liver diseases such as hepatitis A. Autoimmune hepatitis is very rare, the incidence of this disease is about 1.9 / 100,000. But if the condition doesn't improve, autoimmune hepatitis can lead to dangerous and irreversible complications such as cirrhosis and liver cancer.
What is autoimmune hepatitis?
Autoimmune hepatitis (AIH) is liver damage caused by the body's own immune system that attacks liver cells instead of attacking bacteria and other pathogens that invade the body, causing Infection can lead to cirrhosis and liver failure if left untreated

. Autoimmune hepatitis is a chronic, fairly rare, non-infectious disease, but there is no effective way to prevent it.
There are 2 types of autoimmune hepatitis:
Type 1: is the most common type of disease, often develops suddenly, can occur at any age. Up to 50% of people with type 1 autoimmune hepatitis have other autoimmune disorders like rheumatoid arthritis, thyroiditis .



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Type 2: less common, the object of this category is girls from 2-14 years old, can meet in adults.
Autoimmune inflammation occurs when the immune system attacks liver cells instead of pathogens
The cause of autoimmune hepatitis
Autoimmune hepatitis was first discovered by Waldenstrom in 1950 in young patients. The cause of autoimmune hepatitis has not been determined, scientists have not found the exact answer.
This disease may be due to the patient's immune system being unable to distinguish between healthy and harmful body tissues. It can also be caused by an infection, by taking medications, or by genetic factors or habitat affecting the human body.
The risk of autoimmune hepatitis
Gender: Autoimmune hepatitis can be found in both genders and all ages but is more common in women Women make up about 70% of people with autoimmune hepatitis;
History of infection: When the body is exposed to certain types of bacteria, autoimmune hepatitis has the opportunity to develop;
Use some medications: there are some antibiotics that can cause autoimmune hepatitis like minocycline, atorvastatin medicine to treat cholesterol;
Family: The disease is inherited, so you can get it if someone in the family has autoimmune hepatitis;
Having another autoimmune disease: A person is more likely to have autoimmune hepatitis than a normal person if he has or has another autoimmune disease.




Using certain types of antibiotics has a high risk of autoimmune hepatitis
Symptoms of autoimmune hepatitis
Skinnyness, fatigue, and pain in the lower right flank: autoimmune hepatitis begins quietly with mild to severe signs. Common symptoms include fatigue, abdominal discomfort, joint pain, itching, and jaundice. Nosebleeds, root bleeding and subcutaneous hemorrhage are also common manifestations;
Clinical examination: at the early stage of clinical examination, the liver and left lobe are usually larger, in the later stage, the liver is often atrophy and splenomegaly accompanied by lymphadenopathy, ascites, collateral circulation. Allergic capillaries, acne, erythema or scattered erythema;
Blood test: Increased gammaglobuline may be seen. Bilirubin> 3mg / dL, alkaline phosphatase> 2 times, AST> 1000U / L. Autoimmune hepatitis can complicate to pernicious anemia, hemolytic anemia, thrombocytopenic purpura, ulcerative colitis, autoimmune thyroid disease, rheumatoid arthritis. celiac disease, increased venous blood pressure, venous expansion in the esophagus.
Treatment of autoimmune hepatitis
The main treatment for autoimmune hepatitis is the use of prednisone or corticosteroid drugs to prevent the immune system from working excessively.




Can be treated with other immunosuppressant drugs such as Azathioprine (azasan, Imuran) and 6-mercaptopurine if the patient is unable to treat with the above drugs or develop dangerous side effects.
If untreated autoimmune hepatitis can lead to cirrhosis and end-stage liver failure, if the medicine stops treating the disease, the patient will be considered for a liver transplant by a doctor.
Most illness will improve when treated early and properly, but the disease can still recur and some people have to be treated for life.
Patients may need a liver transplant if autoimmune hepatitis progresses to cirrhosis, liver failure
With useful information about autoimmune hepatitis in the content of the above article, it will hopefully help you have a better overview to effectively prevent and treat the disease./..

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