Note When Using Drugs To Treat Irritable Bowel

Irritable bowel syndrome is a functional digestive disorder characterized by symptoms of abdominal pain and changes in bowel habits without any physical damage found. This syndrome is also known by many different terms such as spasm of the colon, irritable colon, nervous nerve ...
Irritable bowel syndrome (HCRKT) is an excluded diagnosis

. There are no specific manifestations of peristaltic or structural disorders, so irritable bowel syndrome is still a clinically defined major pathology. The use of medication is as follows:
Anticholinergic drugs: Antispasmodic drugs, inhibiting smooth depolarization of the intestine at muscarinic receptors.
Dicyclomin hydrochloride: Pain reliever and symptom of bowel movement Very useful for autistic children with diarrhea.




Preventing the effect of acetylcholine on sympathetic receptors in the secretory glands, smooth muscles and central nervous system. Side effects depend on the dose.
Interaction: May increase the anticholinergic effect when used with amantadine, anti-arrhythmic drugs of group I, antihistamines, antipsychotics, benzodiazepines, MAOIs, drugs, nitrates, sympathomimetic drugs, anti- tricyclic depression; dicyclomin can increase serum digoxin levels, antacids may interfere with dicyclomin absorption.
Contraindications: Hypersensitivity history; obstruction of the urinary tract; Severe myasthenia gravis, glaucoma, intestinal obstruction; paralysis of the intestine; Toxic megacolon (toxic megacolon).
Caution: Fetal risk has not been confirmed in human studies but has been shown in some animal studies.
Caution should be used in patients with hepatic or renal impairment, cardiovascular disease, ulcerative colitis, hyperthyroidism or hypertension. The drug may cause drowsiness, constipation, urinary retention, tachycardia, blurred vision, dry mouth or dizziness
Hyoscyamine sulfate: Prevents the effects of acetylcholine at the sympathetic receptors in smooth muscle, the secretory glands and the central nervous system, causing antispasmodic effects.



Reduce symptoms of diarrhea and pain. Useful for the prevalence of HCRKT with diarrhea.
Interaction: May increase the anticholinergic effect when used with amantadine, anti-arrhythmic drugs of group I, antihistamines, antipsychotics, benzodiazepines, MAOIs, drugs, nitrates, sympathomimetic drugs, anti- Tricyclic depression.
The drug may increase the concentration of digoxin in the blood serum. Antacids can interfere with the absorption of hyoscyamine.
Contraindications: Hypersensitivity history; obstruction of the urinary tract; Severe myasthenia gravis, glaucoma, intestinal obstruction; paralysis of the intestine; Poisoned colonic.
Caution: There is a risk to the fetus in animal studies but has not been studied in humans, may be used if the benefits outweigh the risks to the fetus. Use with caution in elderly patients.




Some products containing sodium metabisulfite can cause allergies. The drug may cause drowsiness, constipation, urinary retention, tachycardia, blurred vision, dry mouth or dizziness.
Medicines to treat diarrhea:
Are unabsorbed synthetic opioids. The drug extends the travel time of food through the gastrointestinal tract and reduces secretion through peripheral μ-opioid receptors. The drug reduces the sensation of pain in the internal organs through inhibition of afferent nerve pathways.
Diphenoxylate hydrochloride 2.5mg and atropin sulfate 0.025mg.



The drug combines diphenoxylate, a congener with meperidine, which causes constipation and atropine to prevent abuse.
Inhibiting the pushing and excessive movement of the digestive tract. Medications can make constipation worse.
Interaction: May slow the metabolism of other drugs in the liver. Combined with CNS inhibitors, MAOIs and anti-muscarinic agents may increase the toxicity of the drug; diphenoxylate may enhance the effects of barbiturates, barbiturates, alcohol; Atropine sulfate interacts with MAOIs.
Contraindications: Hypersensitivity history; Narrow-angle glaucoma, liver failure, progressive kidney disease; Pseudomembranous colitis, intestinal intestinal infection.
Caution: There is a fetal risk in animal studies but has not been studied in humans, may be used if the benefit outweighs the risk to the fetus.
In young children, dehydration can affect metabolism, making them more susceptible to slow intoxication with diphenoxylate; Used with caution in patients with ulcerative colitis.




Reduced bowel motility may be harmful to patients suffering from diarrhea caused by Shigella, Salmonella and toxin-producing strains of Ecoli; The drug can cause drowsiness, constipation, urinary retention, tachycardia, blurred vision, dry mouth, dizziness or respiratory depression.
Loperamide: The drug acts to inhibit and slow down the bowel movement, prolong the travel time of water and electrolytes, increase consistency, reduce dehydration and electrolytes.
Over-the-counter medications. Loperamide reduces the frequency of bowel movements and improves stool properties, relieving abdominal pain and having a bowel movement. The drug may cause constipation.
Interactions: Phenothiazine, tricyclic antidepressants, and CNS may enhance lop toxicity..

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