People With Lupus Erythematosus Need To Know

The term lupus erythematosus (lupus erythematosus) has long been used to describe a number of facial diseases such as skin redness, ulcers, and skin atrophy ... In recent years, based on research on the pathogenesis, lesions Basically, clinical progression .

.. It is divided into two types of lupus erythematosus: disk lupus erythematosus and systemic lupus erythematosus.
For people with this condition, new medical advances have been made in treatment, and women who are infected can still give birth if they are closely monitored throughout pregnancy
Discus lupus erythematosus
This is a mild form of lupus erythematosus.



The disease has only skin lesions, no internal injuries. Until now people have not fully understood the pathogenesis of this lupus. However, many factors related to that disease are mentioned such as: genetics, sunshine, bacterial infections and especially local immune disorders.
However, antinuclear antibodies have not been found in the serum, and the complementary concentration in the blood is still normal, so it is thought that the pathogenesis of discus lupus erythematosus and systemic lupus erythematosus is different. .
However, according to some researchers, about 1 - 3% of patients with discus lupus erythematosus during progression may turn into systemic lupus erythematosus. The most common and common skin lesions are localized scaly macules in exposed areas such as the face, neck, hands, etc These lesions are very sensitive to sunlight, if the long-term progression causes atrophy in the middle ( It looks like a disc, so it should be called "disk form").



Some lesions may be hyperplasia.
To treat the disease: with topical corticosteroids such as eumovate, diprosalic or dermovate. Systemic: anti-malarial drugs work very well, but require long-term treatment so it is necessary to monitor vision at least every 3 months.
Systemic lupus erythematosus
Systemic lupus erythematosus is one of the common autoimmune diseases among young women. The disease causes damage to many internal organs such as skin, mucous membranes, liver, kidneys, joints, heart, lungs, nerves ... The pathogenesis of systemic lupus erythematosus is complicated, due to many factors involved.



However, in recent years, the two main, most important factors thought to be directly related to the disease are hereditary and immune disorders.
In addition, a number of other factors influence, make or make the disease worse, they are: endocrine, sunlight, infection. Some drugs such as hydralazine, procainamide, isoniazide, sulfonamide, phenitoin, and penicillamine can cause lupus-like illnesses, making it easy to misdiagnose real lupus. Birth control pills also play a role in starting or aggravating the condition.
In the advanced stage, patients always feel tired, anorexia, thinning, moderate fever.
Systemic lupus erythematosus and pregnant women
Women with systemic lupus erythematosus may also become pregnant and have children. However, because this is a systemic disease, a long-term progression and can be life-threatening, it must be carefully considered and consulted before deciding to become pregnant.
Ideally, 6 months before pregnancy, the patient should have stable treatment, no more symptoms in the internal organs.



During pregnancy, the disease can progress to worse, so patients must be monitored, inpatient treatment in specialized hospitals to avoid complications for both mother and fetus.
Skin and mucous lesions: usually presenting first with butterfly-shaped erythema on the cheeks These boards are very sensitive to sunlight. After a while, the lesions spread to the arms, legs and trunk. In addition, bullae, petechiae may also appear. Oral mucosa, pharynx, pharyngeal ulcer but painless. Blonde hair, easy to break and shed a lot. However, hair can regrow when it is cured.
Internal injuries: liver, kidney, digestive disorders.



There may be myocarditis, endocarditis causing heart failure. Pneumonia and pleurisy are also common and can cause respiratory failure.
Arthritis is a very common manifestation, making it difficult for patients to move and move. In addition, there is anemia, which can reduce all 3 forms: red blood cells, white blood cells and platelets.
Some patients show disorientation, perception, and memory disorders. Sometimes there is a severe headache. Psychiatric symptoms may be aggravated by prolonged high-dose corticosteroids.
Treatment and monitoring for systemic lupus erythematosus
It is necessary to have a proper treatment regimen depending on each stage of disease, especially to maintain the regime of medicine and living regime, to work properly even when the disease has stabilized.




Local treatment: Apply corticosteroid ointments such as eumovate, beprosalic, dermovate ... Patients with Raynaud's syndrome need special treatment regime.
Systemic treatment: Corticoid is still the leading drug to treat systemic lupus erythematosus. The dosage should be different according to the stage of disease, but usually the attack dose is 2-3mg / kg / day.
Depending on the improvement of disease, it may reduce 10mg every 1-2 weeks. Some other immunosuppressant drugs are also used and are very effective such as azathioprin, cyclosporin, mycophenolate mofetil .



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However, when using should be cautious with unwanted effects. In recent years.

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