Synthesis Of 4 Physiological Functions Of The Liver

The liver is an important organ that helps to perform many different functions, each of which performs different tasks to maintain the body's life.
Function of creating bile - helps digest lipid
The bile is produced by the liver, the bile ducts then carry the bile down to store it in the gallbladder, concentrate in the gallbladder and down the duodenum when ingested.
On average, the liver excretes 1 liter of bile a day to lipid emulsify and absorb the vitamins (A, K, D, E) dissolved in oil.
Bile is made up of water, bile salts, cholesterol and bilirubin:
Bile salts (potassium or sodium salts) have a lipid-emulsifying effect and absorption of lipid digestive products, lipid-soluble vitamins.
Cholesterol in bile fluid helps regulate blood cholesterol
Billirubin is formed in the liver by hemoglobin oxidation products in the body and then excreted in bile fluid

. The doctor will diagnose biliary obstruction through bilirubin.
Metabolic function
Glucid metabolism
Glucid from the intestine includes glucose, galactose and fructose, substances that will follow the portal vein to the liver. In particular, the liver will convert fructose and galactose into glucose before use
In addition, the liver converts sugars, fatty acids, glycerol and lactic acid into pyruvic or phosphopyruvic acid and then glucose-6-phosphate, eventually glucose.




Glucid metabolism function of the liver
Lipid metabolism
The liver is the place where lipid metabolism occurs most rapidly and strongly, this process has the effect of synthesizing cholesterol and cetonic synthesis.
Fatty acids from glucid, procid and lipid degradation products are synthesized by the liver, which then is metabolized in the blood supply cycle.
In addition, the liver also synthesizes phospholipids and lipoproteins, which are the major forms of lipid transport for the body.
Protid metabolism
The liver is a part of the body's metabolism and protid stores. Protid metabolism consists of two phases: amino acid metabolism and protein synthesis.
Amino acid metabolism: through 3 processes: carboxyl reduction, amino reduction and amino metabolism (the most important process for the liver to synthesize endogenous amino acids specific to the body)
Protein synthesis: 50% of the protein in the body is produced by liver cells so the ability of the liver to regenerate is very strong.
The liver also has two additional functions: the synthesis of plasma proteins and the synthesis of clotting factors, so when liver failure, blood protein decreases causing swelling, blood clotting disorders are prone to bleeding
Reserve function
Blood reserve
Normally, the liver contains a fairly large amount of blood about 600-700ml.



After the infusion, after a meal, drink plenty of water ... causing blood pressure in the liver vein to increase, the liver may contain about 200 - 400 ml more blood.
And vice versa, the liver shrinks when the body is working or when the volume of blood decreases to put some blood into the circulatory system.
Reserves Gluicid
Glucid in the liver is stored as glycogen, which can be enough to provide energy for the body for several hours.
The liver is also involved in regulating blood sugar through glycogen storage. Blood sugar increases, increasing glycogen synthesis for storage, while when blood sugar levels fall, glycogen dissociation increases to bring glucose into the bloodstream to stabilize blood sugar.




Synthesis of liver function
Iron reserves
The three organs that store iron for the body include the liver, spleen and bones, the amount of iron stored from food or Hb (Hemoglobin) degeneration.
Iron is stored in the liver by ferritin and is delivered to the hematopoietic organ by transferrin produced by the liver.
Stock up on vitamins
The liver has the ability to store a number of vitamins such as A (10 months), D (3-4 months), B12 (1- years) for the body, of which B12 is the most important vitamin.
Anti-toxic function, detoxification
To protect the body, the liver acts as a barrier to prevent harmful elements from entering the digestive tract. The liver reduces toxicity and eliminates some substances that are created during the metabolism of the body.
The liver counteracts poison by 2 mechanisms:
Retaining heavy metals such as copper, lead, mercury ...



will then be discharged
Turns toxins into non-toxic or less toxic substances by chemical reactions that are then excreted via the biliary or renal tract.
Many substances such as bilirubin, alkaloids, phenols, steroid hormones, drugs (antibiotics, aspirin, barbiturates ...) will be combined with glucuronic acid and then discharged in urine or bile fluid..

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