Unwanted Effects Of Theophylin Drug
Born in 1940, theophyllin is a widely used methylxanthin derivative, a bronchodilator for patients with bronchial obstructive pulmonary disease.
Because the toxicity of the drug and the mechanism of disease are better understood, theophyllin is gradually less used in the treatment of the disease. Despite this, theopyllin's role in the treatment of chronic obstructive pulmonary disease is controversial.
In general, theophyllin is recommended for patients with chronic bronchospasm who require prolonged bronchiectasis, patients with nocturnal symptoms, or patients who are hospitalized for asthma.
However, there is some evidence that the long-term use of these substances may reduce the ability to control the disease
Theophyllin is usually prescribed for chronic bronchospasm
Side effects of the drug are usually small, as the absorption of drugs from the lungs into the bloodstream increases, systemic effects become more pronounced.
Cardiovascular side effects can be severe and include palpitations, tachycardia, high blood pressure and arrhythmias.
Local respiratory side effects include coughing, wheezing, breathing disorders, bronchospasm, dry or itchy throat and laryngitis; May cause tremor, dizziness, headache, hot flashes and sweating
Side effects on the central nervous system include staggering, nervousness, agitation and insomnia.
Other side effects include an unusual or unpleasant taste sensation, loss of appetite, hypokalemia, lactic acidosis and sugar.
Theophyllin has a narrow therapeutic range and can cause severe intoxication such as seizures, permanent neurological deficits and death that may occur before the occurrence of mild side effects - this is why it is necessary to monitor serum concentration.
Other serious side effects include tachycardia, arrhythmia, tachypnea and behavioral disturbances in children due to central nervous system stimulation. loaded. The drug causes difficulty in urinating in men with prostatic hypertrophy. Metabolic changes include hyperglycemia and hypokalemia.
Due to the above side effects, theophyllin is now rarely used
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