Covid-19 is causing the world to win the world, but the search, developing an effective antiviral drug against SARS-COV-2 is experiencing a lot of challenges 9: 00/4: 23nam southwalker The restrictions of remdesivir, there are very little reliable antiviral candidates for Covid-19. The design and development of antiviral drugs always require a working process through strict regulations From the initial discovery to study on animals, minimize toxicity and clinical trials on people. Many scientists have noticed warning signs, since SARS appeared in 2003 and Mers in the year 2013 - Both are relatives of SARS-COV-2. As a result, a repository of anti-virus drugs targeting Coronavirus should have been ready. However, when the threat of these two viruses decreases, only spread in some countries, interest and investment in this field of research decreases, making us very little choice in pandemic Currently
. The successful edge is limited by remdesivir, an original drug developed to treat hepatitis C and Ebola, currently still very little reliable antiviral candidates for Covid-19. Medications such as hydroxychloroquine, Ivermectin and several other types, have been expected to be effective, but there are very few data to prove those claims. Difficulties? For decades, many studies have focused on finding new antiviral agents to treat common cold infections to Ebola; And although there have been some success, but the failure is significantly more
So with broad spectrum antibiotics, the effect on many types of bacteria, viruses are very diverse and rapidly developed to the level of methods Effective treatment becomes a very difficult task. Other heads, viruses depend on the host to survive. Basically, they are just genetic matter surrounded in proteins - don't really die or live - and operate by entering the host's cell apparatus to create their own copies to spread Infection. The more depends on their host, the less cell components, leaving less targets with antiviral. This is why vaccine has emerged as a solution Replacing more suitable, in the context of current urgent situation. Instead of directly attacking the virus, vaccine training our body quickly recognizes and eliminates external invaders through the production of antibodies, bonding antibodies and viral disables before it can Self-regeneration. Moreover viruses are highly adaptable. They reproduce very fast and have many opportunities to mutate. For every new generation, it is capable of developing any drug or vaccine that we develop. Which power for a "miraculous" antiviral drug is expected? Although difficult to do, Some antiviral drugs have been successfully studied to treat infections such as HIV, Herpes and Flu
Popular mechanisms include virus prevention before it can penetrate cells, targeting virus shells or breaking its copy cycle. One of the earliest antiviral drugs was developed Acyclovir, acts as a substance that imitates one of the virus protein structure blocks - a nucleoside.virus combines Acyclovir into its developing DNA string during copying, and because acyclovir cannot form links. Exactly, it will end the DNA string before completing.ribavarin, an effective treatment for hepatitis C, also works in the same way, putting mistakes into the genetic code of the virus to do weaken it. Unfortunately, Coronavirus is too "cunning" so that this bait mechanism works completely. It is very difficult to develop a "miraculous" drug that can end or even stop Block a pandemic in the future, mainly because anti-drug viruses are able to grow rapidly. But with investment and ng Scientists are constantly the scientists hope that antiviral drugs can be better positioned to terminate pandemic with other efficient tools such as vaccines, social spacing and masks. In 2021, the US government announced that they would invest more than 3 billion dollars to develop antiviral drugs to treat Covid-19 and prepare for pandemic threats in the future. This money will be used To speed up the process of developing and testing antiviral drugs that have been clinically tested and to detect more medicines, focusing on oral use drugs. Although Vaccine Covid-19 is still important The mind to develop, but antiviral drugs are still the current urgent need. In particular, for people with immune systems that are impossible to be vaccinated, those who are incompletely infected and for those who have not been vaccinated. There are many questions to answer, . Dịch vụ:
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