On October 4, the Nobel Commission announced that the Nobel Prize was born in 2021 - the first award in the Nobel season - belonging to two American biologists David Julius and Ardem PatapouTian with their discoveries on the reception mechanism Temperature and tactile of the human body COUNTRY 9: 00/7: 18 nam nam gioi David Julius (left, photo) and Ardem PatapouTian won the Nobel Patapoutian Medicine 2021 Master David Julius is an American physiologist working At the University of California in San Francisco, Professor Ardem PatapouTian is the Armenian American molecular biologist, working for Scripps Research in La Jolla, California. Before that, these two biologists have received awards about Biology and Medicine of the BBVA Foundation with its research works. How humans feel the temperature and pressure? The ability to feel the heat, cold and tactile of humans is essential to survive And as the foundation for our interaction with the world around. In everyday life, we consider these feelings Sorry, but how do nerve pulses begin to feel temperatures and pressure? This question was resolved by Nobel Winners Yes Born this year. The biologist David Julius has used Capsaicin - a spicy compound from chili causes a hot feeling - to determine a sensor in the ends Nervous skin reacts with heat
. And the biologist Ardem PatapouTian uses sensitive cells to discover the type of sensor that reacts with mechanical stimulus in the skin and internal organs. These breakthroughs have started the activities Intensive research dynamics, helping us know quickly about how human nervous system feels hot, cold and mechanical stimulus. These biologists have identified extremely important relationships on the complex mutual impact between human senses and the environment
One of the major mysteries faced by humanity is a job How people feel their environment. The mechanisms within the senses of the human body have aroused our curiosity for thousands of years, such as how light detected, the sound waves affect our inner ears and ways Different chemical compounds interact with receptors in the nose and mouth creates odors and taste. . .Con who also has countless other ways to perceive the world around, like going barefoot on the grass on a hot summer day can help people feel the heat of the sun, the wind carts And the grass beneath the legs. These senses of temperature, tactile and movement are essential for human adaptation to the surrounding environment that has always changed. A feet touch the ceiling fire will send a mechanical signal to the human brain To know the heat of the 17th century, the René Descartes philosopher envisioned the fibers that connect the different parts of the skin to the brain. Accordingly, a feet touching the ceiling fire will send a mechanical signal to the brain. The discovery has then shown that the existence of symptoms sensitively records changes in human environment. In 1944, 2 scientists Joseph Erlanger and Herbert Gasser have received the Nobel Prize He was born that year for discovering different types of nerve fibers that reacted with different stimuli, such as reacting with painful and painless touches
Since then, people have been Prove that neurons have highly specialized capabilities to detect and convey different types of stimuli, allowing cognitive nuances on human surroundings. Specifically, human ability to feel the difference in the structure of the surface through the fingertips, or the ability to distinguish both pleasant and painful warmth ... .trpv1 and piezo help the human body Feeling the temperature of unknown discoveries in the late 1990s, the biologist David Julius at the University of California, San Francisco (USA) conducted analysis of capsaicin chemical compounds caused a burning feeling that people Feeling when exposed to chili.Capsaicin has been known to be the activation of nerve cells causing pain feeling, but how this chemical actually functions this function is a unneated question A.Julius and colleagues have created a library of millions of DNA paragraphs corresponding to the genes expressed in feeling nerve cells that can react with pain, heat and touch.Julius and copper The karma hypotheses that the library will include a paragraph that encodes protein that can react with Capsaicin. They simulate individual genes in cultured cells often do not react to Capsaicin. After a strenuous search, scientists have identified a single gene that can make cells sensitive to capsaicin. This gene, is determined to encrypt a new ion channel protein and capsaicin receptor, named TRPV1. The detection of TRPV1 is a big breakthrough, leading the way for . Dịch vụ:
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